The influence of plateau on 24 h ambulatory blood pressure of healthy young males / 军事医学

Objective To study the differences in 24 h ambulatory blood pressure of healthy young men between the plateau and the plains.Methods A total of 100 young men were enrolled in this study.They underwent 24 h ambulatory blood pressure monitoring on the plateau and on the plains respectively.The data was analyzed by SPSS.17.Results The 24 h mean systolic blood pressure (24HMSBP) and diastolic blood pressure (24HMDBP),day (6:00-22:00) mean systolic blood pressure (DMSBP) and diastolic blood pressure (DMDBP),night (22:00-6:00) mean systolic blood pressure (NMSBP) and diastolic blood pressure (NMDBP),24 h mean heart rate (24MHR),HRmax,HRmin,24 h systolic blood pressure load (24HSBPL) and diastolic blood pressure load (24HDBPL),day (6:00-22:00) systolic blood pressure load (DSBPL) and diastolic blood pressure load (DDBPL),night (22:00-6:00) systolic blood pressure load (NSBPL) and diastolic blood pressure load (NDBPL) were significantly different between the plateau and plains (all P ＜ 0.05).However,the systolic blood pressure decrease rate (SBPDR) and the diastolic blood pressure decrease rate (DBPDR),day systolic blood pressure coefficient of variation (DSBPCV) and diastolic blood pressure coefficient of variation (DBPCV),night systolic blood pressure coefficient of variation (NSBPCV) and diastolic blood pressure coefficient of variation (NBPCV) were not significantly different (P ＞ 0.05).Conclusion The systolic blood pressure (SBP)and diastolic blood pressure (DBP) on the plateau are significantly higher than those on the plains.24HMDBP and DMDBP increase more significantly on the plateau than those of SBP.The blood pressure load (BPL) on the plateau is higher than that on the plains,with a higher degree of dispersion,so are the 24 h mean heart rate (24MHR),HRmax,and HRmin.

Hemangioma and vascular malformation of small intestine: a clinicopathologic analysis of fifty-one cases / 中华病理学杂志

<p><b>OBJECTIVE</b>To investigate the clinicopathologic features of small intestinal hemangioma and vascular malformation.</p><p><b>METHODS</b>A retrospective analysis was performed on 51 cases of hemangioma and vascular malformation involving the duodenum, jejunum and ileum in the past 30 years.</p><p><b>RESULTS</b>The patient's age ranged from 1.4 to 75.0 years, with an average/median age of 40 years for the 51 cases. The ratio of male and female was almost equal. In most cases, the lesions were located in the ileum (18 cases) and jejunum (16 cases) accounting for 66.7%. The predominant symptoms and signs were either intestinal hemorrhage or obstruction. Grossly, the lesions appeared as polyp-like, ulcerative, varices, solitary mass, diffuse infiltration or in an occult status. Histologically, arteriovenous hemangioma also called arteriovenous malformation was more common seen accounting for 86.3%. Other less common vascular lesions included cavernous hemangioma, capillary hemangioma, Rendu-Osler-Weber syndrome and Dieulafoy disease.</p><p><b>CONCLUSIONS</b>Histologic classification and denomination for hemangioma and vascular malformation of small intestine are still controversial. It is very important to correlate clinical manifestations with arteriography findings in histologic diagnosis of hemanigoma and vascular malformation of the small intestine.</p>

Study with large slice technique and tissue microarray on lymph node involvement and micro-metastasis of rectal cancer / 中华胃肠外科杂志

<p><b>OBJECTIVE</b>To study lymph node involvement and micro-metastasis of rectal cancer with large slice technique and tissue microarray.</p><p><b>METHODS</b>Large slice technique, combined with tissue microarray,was used in pathologic study of 31 patients after total mesorectal excision (TME) for rectal cancer.</p><p><b>RESULTS</b>Nine hundred and ninety- two lymph nodes were harvested and 148 were positive. More than 40% of positive lymph nodes were located in the outer layer of the mesorectum and in the same side of the mesorectum as the primary tumor was. Circumferential margin involvement was observed in 12 cases and correlated with the numbers of metastatic lymph nodes (Beta =1.166, P=0.041). Micrometastasis was found in 9 cases with negative pathological lymph nodes, but not correlated with tumor differentiation and stage (P> 0.05).</p><p><b>CONCLUSION</b>Large slice technique combined with tissue microarray facilitates the detection of lymph node involvement and micrometastasis. There is a predominance of lymph node metastasis in the outer layer and the same side of the mesorectum. Micrometastasis can be discovered in different stages of rectal cancer.</p>